Effects and Benefits of Ketamine-Assisted Psychotherapy

Everyone’s psychedelic experience will be different and can be affected by preparation and intention going into the experience, environmental setting during the experience, trust in those facilitating the experience, and integration of revelations following the experience.

We aim to walk you through every step of your journey so you can enjoy the positive, transformational effects of Ketamine-Assisted Psychotherapy (KAP), whether you experience small incremental progress or a significant breakthrough.

Some describe KAP as condensing 5 years of talk therapy into an hour. Because ketamine affects different areas of the brain compared to traditional SSRIs and actually repairs damage to the prefrontal cortex, it allows for profound breakthroughs and change. More about the science behind ketamine here [link to science page].

Yale’s research into ketamine found that chronically depressed patients who were given ketamine therapy experienced almost immediate relief from symptoms of depression. 

Dr. Joshua Berman, the medical director for interventional psychiatry at Columbia University, leads the department’s ketamine program. His research has found that ketamine’s effects are often immediate, as opposed to SSRIs that may take up to 2 months to determine if they have any effect at all.

Neurobiological side effects

Overall, ketamine is safe to use for most people. Our clinicians ensure it’s a safe form of therapy prior to prescribing. Ketamine acts on the nervous system, so it’s important to block recovery time after your experience. We aim to reduce any side effects by prescribing the proper dosage, however, everyone’s experience is unique. 

Short-term neurobiological side effects may include:

  • Elevated blood pressure
  • Increased heart rate
  • Nausea
  • Drowsiness
  • Disorientation
  • Headache

Long-term neurobiological side effects are most prominent in those who have habitual, recreational use of ketamine, not under clinical supervision. Ketamine does impact the kidneys in particular.

Long-term neurobiological side effects may include:

  • Kidney damage
  • Trouble with urination
  • Substance dependence
  • Respiratory depression
  • Seizures
  • Baseline increase in heart rate
  • Baseline increase in blood pressure

Psychological side effects

Ketamine is a conscious-altering agent and can have a profound effect on your mental health. Research shows that most effects are positive, however, there is always a chance adverse effects could surface. Our comprehensive process is structured to not only help you integrate insights into your daily life, but also manage any distress from processing emotions or memories.

Curious to see if ketamine can support your mental health journey. Fill out a brief assessment and connect with a Curio clinician.


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